Ovarian sex cord-stromal tumors: an update on clinical features, molecular changes, and management
نویسندگان
چکیده
منابع مشابه
Genetics and genomics of ovarian sex cord-stromal tumors.
Ovarian sex cord-stromal tumors (SCST) represent approximately 8% of malignant ovarian tumors. The most common are granulosa cell tumors (GCT) which account for approximately 90% of malignant SCST. Recent studies have unraveled the key genomic and genetic events contributing to their pathogenesis. SCST are found in the hereditary syndromes: Peutz-Jeghers syndrome, Ollier disease and Maffucci sy...
متن کاملOvary: Sex cord-stromal tumors
There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterised by multiple gastrointestinal hamartomatous polyps, increased risk of various neoplasms, and melanocytic macules of the lips, buccal mucosa...
متن کاملOvarian Sex Cord-Stromal Tumors in Postmenopausal Women and Total Laparoscopical Management
BACKGROUND: Ovarian sex-cord stromal tumors (SCST) take up 5% of the ovarian neoplasm and may develop into an ovarian mass or a haemoperitoneum. The surgical management of SCST in early-stage adult patients is not well defined. CASE REPORT: A 69 year-old postmenopausal woman was admitted for metrorrhagia, a right ovary mass and increasing pelvic pain. Preoperative clinical and instrumental exam...
متن کاملSex cord stromal tumors-unusual presentations.
OBJECTIVES The sex cord stromal tumors (SCST) account for approximately 7% of all malignant ovarian tumors. They are endocrinologically active tumors of which granulosa cell tumors are the commonest. We describe an analysis of all cases of SCST managed, in our department over the last five years and discuss two cases of unusual presentation of these tumors. METHODS Ten cases of SCST which wer...
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Ovaries are the female organs that age more quickly than other tissues such as the uterus, the pituitary gland or pancreas. Different from males, an interesting question is why and how the females lose fertility so rapidly. During the aging process, both the number and quality of the oocytes in the ovaries decrease and reach to a point beyond that no more viable offspring may be produced and th...
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ژورنال
عنوان ژورنال: International Journal of Gynecologic Cancer
سال: 2021
ISSN: 1048-891X,1525-1438
DOI: 10.1136/ijgc-2020-002018